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Alejandro San Martín |
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![]() PUBLICACIONES SELECCIONADAS
Imaging Mitochondrial Flux in Single Cells with a FRET Sensor for Pyruvate. PLoS ONE 9(1): e85780. doi:10.1371/journal.pone.0085780
San Martín A, Ceballo S, Baeza-Lehnert F, Lerchundi R, Valdebenito R, Contreras-Baeza Y, Alegría K. and Barros LF. (2014).
Small is fast: astrocytic glucose and lactate metabolism at cellular resolution. Front. Cell. Neurosci. 7:27. doi: 10.3389/fncel.2013.00027
Barros LF, San Martín A, Sotelo-Hitshfeld T, Lerchundi R, Fernández-Moncada I, Ruminot I, Gutiérrez R, Valdebenito R, Ceballo S, Alegría K, Baeza-Lehnert F and Espinoza D (2013).
A Genetically Encoded FRET Lactate Sensor and Its Use To Detect the Warburg Effect in Single Cancer Cells. PLoS ONE 8(2): e57712. doi:10.1371/journal.pone.0057712.
San Martín, A., Ceballo, S., Ruminot, I., Lerchundi, R., Frommer, W.B., and Barros et al. (2013).
Fast and reversible stimulation of astrocytic glycolysis by K+ and a delayed and persistent effect of glutamate. J Neurosci. 2011 Mar 23;31(12):4709-13.
Bittner CX, Valdebenito R, Ruminot I, Loaiza A, Larenas V, Sotelo-Hitschfeld T, Moldenhauer H, San Martín A, Gutiérrez R, Zambrano M, Barros LF.
Tacrolimus causes a blockage of protein secretion which reinforces its immunosuppressive activity and also explains some of its toxic side-effects
Rauch MC, San Martín A, Ojeda D, Quezada C, Salas M, Cárcamo JG, Yañez AJ, Slebe JC, Claude A. Transpl Immunol. 2009 Dec;22(1-2):72-81PATENTES
Patent application, Genetically encoded probe for quantification of lactate with high spatial and temporal resolution, and methods for quantifying metabolic rates and lactate transport using the same. International application number PCT/US12/33639.
San Martín, A., Ceballo, S., Frommer, W.B. & Barros, L.F. (2012)
Patent application, Genetically encoded probe for quantification of pyruvate concentration with high spatial and temporal resolution, and methods using the same for quantifying pyruvate transport, cellular pyruvate production and consumption, and mitochondrial pyruvate consumption in intact cells. Application number: PCT/IB2013/056766.
San Martín, A., Ceballo, S. & Barros, L.F. (2013)PRESENTACIONES EN CONGRESOS
A genetically-encoded FRET sensor for lactate: a new tool for cancer drug discovery. Center for Scientific Studies (CECs), Valdivia, University Austral of Chile, Valdivia, & Carnegie Institution of Wahington. Dubai, UAE, 2013. 5th International Conference on Drug Discovery & Therapy.
San Martín, A., Ceballo, S., Ruminot, I., Lerchundi, R., 3Frommer, W.B. & Barros, L.F.
New methods for the study of lactate metabolism with a genetically encoded FRET nanosensor. Center for Scientific Studies (CECs), Valdivia, University Austral of Chile, Valdivia, & Carnegie Institution of Wahington. Bacelona, Spain, 2012. Multidisciplinary approaches to quantify astrocyte neuron signaling.
San Martín, A., Ceballo, S., Ruminot, I., Lerchundi, R., Frommer, W.B. & Barros, L.F.
XXV Annual meeting of the chilean society for cell biology. LACONIC, a genetically encoded FRET nanosensor for lactate. Center for Scientific Studies (CECs), Valdivia, University Austral of Chile, Valdivia, Carnegie Institution of Wahington, 2011.
San Martín, A., Ceballo, S., Frommer, W.B.; Barros, L.F.
XXII Annual meeting of the chilean society for cell biology. “No catalitic region of hGBF-1 are essencial for his localitation and function in the secretory pathway”. Institute of Biochemistry, University Austral of Chile, Valdivia, Chile, 2008.
San Martín, A., Rauch, M.C. y Claude, A.
III International meeting of Farmacology y Therapéutic. Cuban society of Farmacology. Diabetogenic effect of immunosuppressive drugs FK506 by blocking insulin secretion in pancreatic cells. La Habana, Cuba, 2007.
Rauch, M.C., San Martín, A., Ojeda, D., Quezada, C., Salas, M., Cárcamo, J.G., Yánez, A.J., Slebe, J.C. y Claude, A
XX Annual meeting of the chilean society for cell biology. “Análisis de la función de hGBF-1 y hBIG-1 mediante el silenciamiento por siRNA y construcción de proteínas quiméricas”. Institute of Biochemistry, University Austral of Chile, Valdivia, Chile, 2006.
San Martín, A., Rosas, J., Rauch, M.C. y Claude, A.
CONTACTO
Teléfono : +56-63-234524
Fax : +56-63-234517
Correo Electrónico :lc.scec@ojelaa
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