ICBEM - International Conference on Brain Energy Metabolism

Speakers ICBEM 2018

Detlev Boison
Legacy Research Institute, USA
Juan Bolaños
Universidad de Salamanca, Spain
Felipe Court
Universidad Mayor, Chile
Gerald Dienel,
University of Arkansas, USA
Kelly Drew
University of Alaska Fairbanks, USA
Jordi Durán
IRB Barcelona, Spain
Alexander Gourine
University College London, UK
Sandra Hewett
Syracuse University, USA
Hajime Hirase
RIKEN, Japan
Tibor Kristian
University of Maryland, USA
Jakob Nissen
University of Copenhagen, Denmark
Pierre-Yves Placais
CNRS-ESPCI, France
Caroline Rae
University of South Wales, Australia
Margaret Rice
New York University, USA
Claire Rittschof
University of Kentucky, USA
Mike Robinson,
University of
Pennsylvania, USA
Zu-Hang Sheng
NIH, USA
Charlotte Stagg
University of Oxford, UK
Ray Swanson
University of California San Francisco, USA
Marcelo Vargas
University of South Carolina, USA
Sergei Vinogradov
University of Pennsylvania, USA
Gary Yellen
University of Harvard, USA

It is our great pleasure to invite you to the 13th International Conference on Brain Energy Metabolism entitled, "How Metabolism Dictates Neurotransmission, Function and Behavior", which will be held at the Centro de Estudios Científicos CECs, Valdivia, Chile, on March 7-10, 2018.

Our aim is to bring together a select group of leading experts, clinicians, emerging young scientists and students interested in brain energy metabolism. Lectures and discussions will cover latest developments in research related to metabolite trafficking, enzyme and transporter regulation, brain cell heterogeneity, new in vitro and non-invasive imaging techniques, and the tight reciprocal coupling between brain energy metabolism and information processing.

Traditionally, these meetings provide a forum for very lively and informative discussions after the talks and during free time and poster sessions. Student and fellow participation is strongly encouraged, and travel awards for a limited number of young scientists will be available.

The conference will be held at the Carpa de la Ciencia of the Centro de Estudios Científicos, located in the scenic and historic city of Valdivia, 800 km south of Santiago. Registration covers hotel accommodation, meals and other expenses, including an excursion to a temperate forest reserve, boat trip and farewell dinner.

Women, minorities, and persons with disabilities are especially encouraged to participate in the Brain Energy Metabolism meeting. Any participants who have special needs are requested to make their requirements known to the organizers so that every effort can be made to address these needs.

We are looking forward to meeting you in Valdivia in March 2018.

L. Felipe Barros
Mary McKenna
On behalf of the Organizers

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Registration

The meeting registration fee is US$ 880 for participants, US$280 for guests over age 14, and US$ 620 for students. All costs are per person and include conference registration, 4 nights hotel accommodation, opening reception, most meals, an excursion to a temperate forest reserve, boat trip and farewell dinner.

The Registration links (below) will open a Word or a PDF registration form. Please return the completed registration form labelled with your name as a PDF file (E.g. SmithMary.pdf) to Ms. Loreto Fernandez at ICBEM@cecs.cl You will receive instructions for payment within 48 hrs, which will be done through a secure commercial credit card server or, alternatively, through wire transfer.

Refund Policy: Registration costs will be 90% refunded until February 20^th. We will not be able to refund registration costs after February 20^th.

Download Registration Form (Word)

Download Registration Form (PDF)

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Abstract Submission

Abstract submission requires previous registration (use link below for instructions). Deadline for abstract submission is Friday December 15^th 2017 for all participants.

Download Abstract Submission Form

Poster guidelines

The poster must be in vertical format. It should not exceed the following dimension: 130 cm height, 90 cm width. Fixing material will be provide on-site at the poster help desk.

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Travel Award Application

Travel awards of up to US$ 1,000 depending on geographical location will be granted to selected graduate students and postdocs that submit an abstract. To apply for a Travel Award, you must first register using the above link. Please enclose a personal letter explaining why you want to participate in ICBEM Valdivia 2018, and a supporting letter from your advisor/head of laboratory. Please send all documents to Ms. Loreto Fernandez at ICBEM@cecs.cl by December 15^th 2017.

Decisions about Travel Awards will be communicated by Friday January 12^th 2018.

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Scientific Program

Wednesday, March 7^th 2018

15:00-17:50   Registration (and put up ALL posters, odd and even numbers)
18:00-18:15   Welcome: L. Felipe Barros (Chile)
18:15-18:25   Words from Dieter Uslar (Colun SA, Chile)
18:25-19:25   Plenary Lecture

Gerald A. Dienel (USA)

Aerobic glycolysis during brain activation

Gerald A. Dienel (USA)

Chairs: Mary McKenna (USA) and Ignacio Fernández-Moncada

(Chile)
19:25-19:35 A Tribute to Leif Hertz (1930-2018)

Arne Schousboe (Denmark) and Mary McKenna (USA)
19:35-21:30 Opening Reception

Thursday, March 8^th 2018

08:45-09:10 25 Years of ICBEM History

Mary McKenna (USA)
09:10-10:40 O2 metabolism & sensing

Chairs: Bruno Weber (Switzerland) and Elisa York (Canada)

S1: Sergey Vinogradov (USA)

Dynamic imaging of oxygen in the brain

S2: Alexander Gourine (UK)

Astrocytes as CNS metabolic sensors

S3: Ray Swanson (USA)

Bioenergetic regulation of microglia
10:40-11:00 Coffee break
11:00-13:00 Student awardee presentations

Chairs: Michael Robinson (USA) and Gilles Bonvento (France)

Anna Hadjihambi (UK), Antoine Cherix (Switzerland),

Elisa York (Canada), Emil Jakobsen (Denmark),

Marianne Maugard (France), Ernesto Miquel (Uruguay),

Nina Klimova (USA), Felipe Baeza Lehnert (Chile),

Zoe Looser (Switzerland), Jens Andersen (Denmark),

Sarah Rice (USA), Ignacio Fernández-Moncada (Chile)
13:00-14:30 LUNCH
14:30-15:30 Students/postdoc pitches "Why you should come to my poster"

Chairs: Kelly Drew (USA) and Jens Andersen (Denmark)
15:30-17:30 Bioenergetics and mitochondrial metabolism

Chairs: Sandra Hewett (USA) and Iván Ruminot (Chile)

S4: Caroline Rae (Australia)

Acetate and β-hydroxybutyrate in brain metabolism

S5: Charlotte Stagg‡ (UK)

Role of glutamate/GABA/glutamine metabolism in brain plasticity and

neurological recovery

S6: Jakob Nissen‡ (Denmark)

Is glutamate metabolism via glutamate dehydrogenase important for

brain mitochondrial metabolism?
17:30-19:30 Poster session I (odd numbers) with coffee, wine and cheese

Friday, March 9^th 2018

09:00-11:00 Mitochondrial trafficking

Chairs: Arne Schousboe (Denmark) and Mariane Maugard (France)

Special Imaging Talk (40 min + 20 min discussion)

Zu Hang Sheng (USA)

Mitochondrial transport and energy homeostasis in neuronal

degeneration and regeneration

S7: Mike Robinson (USA)

Physiologic and pathologic implications of functional interactions

between astrocytic glutamate transport, calcium, and mitochondria

S8: Gary Yellen (USA)

Neuronal metabolic response to stimulation studied with fluorescent

biosensors
11:00-11:20 Coffee break
11:20-12:20 Mitochondria/energy production/ROS

Chairs: Johannes Hirrlinger (Germany) and Zoe Looser

(Switzerland)

S9: Juan Bolaños (Spain)

The mitochondrial oxidative phosphorylation organization in neurons

and astrocytes determine brain redox bioenergetics

S10: Margaret Rice (USA)

Dynamic regulation of neuronal activity and transmitter release
12:20-13:40   LUNCH
13:40-18:30   Afternoon Excursion
18:30-20:30   Evening discussion groups and dinner

Session organizers: Ray Swanson (USA) and Blanca Aldana

(Denmark)
20:30-22:30 Poster session II (even numbers) with coffee, wine and cheese

Saturday, March 10^th 2018

09:00-10:30 NAD⁺ homeostasis and salvage pathways

Chairs: Caroline Rae (Australia) and Carlos Díaz-García (USA)

S11: Tibor Kristian (USA)

Multi-targeted effect of nicotinamide mononucleotide in amelioration

of ischemic brain damage

S12: Felipe Court (Chile)

Schwann cell exosomes mediate neuronâ€“glia communication and

enhance axonal regeneration

S13: Marcelo Vargas (USA)

Enhancing NAD+ salvage in astrocytes to prevent astrocyte-mediated

motor neuron death
10:30-10:50 motor neuron death
10:50-11:50 Glycogen role and relationship to glucose metabolism and

neurotransmission

Chairs: Joao Duarte (Sweden) and Louis-Philippe Bernier (Canada)

S14: Hajime Hirase (Japan)

Brain glycogen distribution by glycogen immunohistochemistry in the

mouse

S15: Jordi Duran (Spain)

Glycogen metabolism in astrocytes and neurons
11:50-13:20 LUNCH
13:20-14:50 Neuronal - glial interactions modulating neurotransmission,

wakefulness and injury

Chairs: Susanna Scafidi (USA) and Kelly Chamberlain (USA)

S16: Detlev Boison (USA)

Adenosine and A2A receptor modulation of neuronal-glial interactions

and synaptic plasticity

S17: Kelly Drew (USA)

Seasonal rhythm in A1 adenosine receptor signaling in hibernation

S18: Sandra Hewett (USA)

System xc- exacerbates striatal symptomology and pathology

induced by systemic administration of 3-nitroproprionic acid in female

mice
14:50-15:15 Coffee break
15:15-16:15 How metabolism influences behavior

Chairs: Yuri Zilberter (France) and Maria Eugenia Guitart

(Argentina)

S19: Claire Rittschof‡ (USA)

Honey bee aggression: brain energy metabolism predicts behavior

and responds to social cues

S20: Pierre-Yves Plaçais‡ (France)

An upregulation of energy metabolism in the Drosophila mushroom

body triggers long-term memory formation
16:15-16:45 Postdoc awardee presentations

Chairs: L. Felipe Barros (Chile) and Mary McKenna (USA)

P14 Carlos Díaz-García (USA)

Synaptic stimulation increases glucose utilization in dentate granule

neurons

P10 Kelly Chamberlain (USA)

Axon-glial interactions: oligodendrocyte-mediated enhancement of

axonal [ATP] in health and injury

P8 Louis-Philippe Bernier (Canada)

Rapid plasticity of microglial metabolism sustains immune surveillance

of the brain parenchyma
16:45-17:00   Closing comments and evaluation
17:00-17:10   14^th ICBEM meeting information Gerald A. Dienel (USA)
18:10-22:00    Boat ride and Farewell Dinner

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Practical Information

Child care will be available. Please let us know of your specific needs to make the necessary arrangements.

Participants who have special needs, dietary or other, are invited to make their requirements known to the organizers so that every effort can be made to address these needs.

Travelling

Valdivia Airport is not international, so you will have to fly through Santiago Airport (SCL), which receives direct flights from several international hubs including Miami, Atlanta, Dallas, Toronto, Madrid, London, Paris, Frankfurt, Rome, Mexico City, Sidney, Sao Paulo, Buenos Aires, etc. Most flights from Europe, North America, and Oceania arrive in Santiago during the morning.

Connecting flights from Santiago to Valdivia Airport (ZAL) last about 1.5 hours and are usually scheduled around midday. Valdivia Airport is located 25 km north of Valdivia and is well connected to the city by shuttles (USD 6). Early March is still high season, so it is strongly advised to book your flight well in advance (i.e. by November 2017). Otherwise you may have to fly to Temuco (ZCO) or Osorno (ZOS), which are about 100 km of Valdivia. The 2 hour taxi ride from Temuco or Osorno Airport to Valdivia costs about USD 80.

Alternatively, overnight coaches (buses) from Santiago to Valdivia charge between USD 15 (a reclinable seat leading to swollen feet) and USD 50 (very confortable fully horizontal bed).

Car rentals. Car rentals are available at the airports.

Visa Application Nationals from most countries can enter Chile for up to 90 days without a Visa.

For specific details check https://en.wikipedia.org/wiki/Visa_policy_of_Chile

Links to the airlines that fly to Valdivia (LATAM and Sky) and to the main bus operator (Turbus):

LATAM
Sky
Turbus

Climate

Early March is late summer in Valdivia. Average temperatures are 21 ºC (70ºF; high) and 10 ºC (50ºF; low). The chance of rain is 16%. More information can be found in https://weatherspark.com/y/24136/Average-Weather-in-Valdivia-Chile

Time Zone is UTC/GMT - 3 hours.

Other

1 US dollar = 660 Chilean Pesos (as of April 2017)
Power supply: 220 V / 50 Hz, plugs type C/L

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